WNT1 Mouse Monoclonal Antibody [Clone ID: 10C8]

CAT#: AM06361SU-N

WNT1 mouse monoclonal antibody, clone 10C8, Ascites


USD 395.00

2 Weeks*

Size
    • 100 ul

Product Images

Specifications

Product Data
Clone Name 10C8
Applications ELISA, FC, IF, IHC, WB
Recommended Dilution Western Blot: 1/500 - 1/2000.
Immunohistochemistry on paraffin sections: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: 1/10000.
Reactivities Human, Mouse
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Purified recombinant fragment of WNT1 expressed in E. Coli.
Specificity This antibody reacts to WNT1.
Formulation State: Ascites
State: Ascitic fluid containing 0.03% sodium azide.
Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Stability Shelf life: one year from despatch.

Predicted Protein Size 41 kDa
Background WNT1: wingless-type MMTV integration site family, member 1. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant rolein Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.
Synonyms Proto-oncogene protein Wnt-1, INT1, INT-1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.