ROR1 Mouse Monoclonal Antibody [Clone ID: 2H6]

CAT#: AM06399SU-N

ROR1 mouse monoclonal antibody, clone 2H6, Ascites


USD 395.00

2 Weeks*

Size
    • 100 ul

Product Images

Specifications

Product Data
Clone Name 2H6
Applications ELISA, IF, WB
Recommended Dilution ELISA: 1/10000. 
Western Blot: 1/500-1/2000.
Immunofluorescence: 1/200-1/1000.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Recombinant extracellular fragment of human ROR1 (aa30-406) fused with hIgGFc tag, expressed in HEK293 cells
Specificity Recognizes Human ROR1.
Other species not tested.
Formulation State: Ascites
State: Ascitic fluid
Preservative: 0.03% Sodium Azide
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Stability Shelf life: one year from despatch.

Predicted Protein Size 101 kDa
Background ROR1, a type I membrane protein, is a receptor protein tyrosine kinase that modulates neurite growth in the central nervous system. The ROR-family receptor tyrosine kinases consist of two structurally related proteins, ROR1 and ROR2. These proteins are characterized by having intracellular tyrosine kinase domains, which are highly related to Trk-family kinases, extracellular Frizzled-like cysteine-rich domains (CRDs) and Kringle domains. The ROR family members are highly conserved among species, such as C. elegans, Drosophila, Xenopus and mammals. ROR1 and ROR2 are both involved in organogenesis with particular emphasis in neuronal differentiation. Increased expression of ROR1 in acute lymphoblastic leukemias (ALLs) as well as chronic lymphocytic leukemias (CLLs) implicate this protein as a potential tool for targeted immunotherapy in these diseases.
Synonyms NTRKR1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.