MEK4 (MAP2K4) Mouse Monoclonal Antibody [Clone ID: 5H4]

CAT#: AM06580SU-N

MEK4 (MAP2K4) mouse monoclonal antibody, clone 5H4, Ascites


USD 425.00

2 Weeks*

Size
    • 100 ul

Product Images

Specifications

Product Data
Clone Name 5H4
Applications ELISA, FC, IHC, WB
Recommended Dilution ELISA: 1/10000.
Western Blot: 1/500 - 1/2000.
Flow Cytometry: 1/200 - 1/400.
Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Purified recombinant fragment of Human MAP2K4 expressed in E. Coli.
Specificity Recognizes MAP2K4
Formulation State: Ascites
State: Ascitic fluid containing 0.03% Sodium Azide.
Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Stability Shelf life: one year from despatch.

Predicted Protein Size 42 kDa
Background This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.Tissue specificity: Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues .
Synonyms JNK-activating kinase 1, MAP Kinase Kinase 4, SAPK/ERK kinase 1, PRKMK4, SERK1, MEK-4, MAPKK4, MKK4
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.