CEBP Beta (CEBPB) Mouse Monoclonal Antibody [Clone ID: 3H9]
Specifications
Product Data | |
Clone Name | 3H9 |
Applications | ELISA, FC, WB |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of human CEBPB expressed in E. Coli. |
Specificity | This antibody reacts to CEBPB. |
Formulation | State: Ascites State: Ascitic fluid containing 0.03% sodium azide. |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 36 kDa |
Database Link | |
Background | The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. Tissue specificity: Expressed at low levels in the lung, kidney and spleen. |
Synonyms | C/EBP beta, TCF5, LAP, NF-IL6 |
Reference Data |
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