LRP5 Mouse Monoclonal Antibody [Clone ID: 2B11]
Specifications
Product Data | |
Clone Name | 2B11 |
Applications | ELISA, FC, WB |
Recommended Dilution | ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Flow Cytometry: 1/200 - 1/400. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of Human LRP5 expressed in E. Coli. |
Specificity | Recognizes LRP5 |
Formulation | PBS State: Purified State: Liquid purified IgG fraction Stabilizer: 0.5% protein stabilizer Preservative: 0.05% Sodium Azide |
Concentration | lot specific |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 179 kDa |
Gene Name | LDL receptor related protein 5 |
Database Link | |
Background | This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. |
Synonyms | LRP7, LRP-5 |
Reference Data |
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