Cd2 Rat Monoclonal Antibody [Clone ID: 12-15]

CAT#: AM08025FC-N

Cd2 rat monoclonal antibody, clone 12-15, FITC

Product Images

Immunofluorescent Staining: BALB/c lymph node cells were stained with Rat anti-Mouse CD2-FITC (Cat#AM08025FC). Lymphocytes were then gated and analyzed by flow cytometry. Amount Used: 1 ug/10e6 cells.

Specifications

Product Data

• Clone Name: 12-15
• Applications: FC
• Recommended Dilution: Flow Cytometry < / = 1 µg/10e6 cells. (Ref.1-3)
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG1
• Clonality: Monoclonal
• Specificity: This antibody is specific to CD2/LFA-2 (Mr 45-58 kDa)
• Formulation: PBS containing 0.09% Sodium Azide as preservative.
  Label: FITC
  State: Liquid purified Ig fraction.
  Label: Fluorescein Isothiocyanate Isomer 1
• Concentration: 0.5 mg/ml
• Conjugation: FITC
• Database Link:
  Entrez Gene 12481 Mouse
• Background: CD2, also known as leukocyte function-associated antigen-2 (LFA-2), is a member of the immunoglobulin superfamily of cell adhesion molecules. (Ref.1) It is expressed on the surface of >95% of thymocytes, and essentially all B cells, T cells and NK cells. (Ref.1-3) In the mouse, CD2 is the receptor for CD48. (Ref.4) CD2 is thought to play a major role in mediating T-cell adhesion, T-cell recognition/activation, T-cell signaling and intrathymic differentiation. (Ref.5-10)
• Synonyms: SRBC, Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor