Cd2 Rat Monoclonal Antibody [Clone ID: 12-15]
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Specifications
Product Data | |
Clone Name | 12-15 |
Applications | FC |
Recommended Dilution | Flow Cytometry < / = 0.5 µg/10e6 cells. (Ref.1-3) |
Reactivities | Mouse |
Host | Rat |
Isotype | IgG1 |
Clonality | Monoclonal |
Specificity | This antibody is specific to CD2/LFA-2 (Mr 45-58 kDa) |
Formulation | PBS containing 0.09% Sodium Azide as preservative and a stabilizing agent. Label: PE State: Liquid purified Ig fraction. Label: R-Phycoerythrin |
Concentration | 0.1 mg/ml |
Conjugation | PE |
Database Link | |
Background | CD2, also known as leukocyte function-associated antigen-2 (LFA-2), is a member of the immunoglobulin superfamily of cell adhesion molecules. (Ref.1) It is expressed on the surface of >95% of thymocytes, and essentially all B cells, T cells and NK cells. (Ref.1-3) In the mouse, CD2 is the receptor for CD48. (Ref.4) CD2 is thought to play a major role in mediating T-cell adhesion, T-cell recognition/activation, T-cell signaling and intrathymic differentiation. (Ref.5-10) |
Synonyms | SRBC, Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor |
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