Cd3e Rat Monoclonal Antibody [Clone ID: C363.29B (YCD3-1)]

CAT#: AM08026FC-N

Cd3e rat monoclonal antibody, clone C363.29B (YCD3-1), FITC


USD 350.00

3 Days*

Size
    • 500 ug

Product Images

Specifications

Product Data
Clone Name C363.29B (YCD3-1)
Applications FC
Recommended Dilution Flow Cytometry: Identification and enumeration of CD3+ (≤ 3 µg/106 cells) (See also Ref.1,2).
Reactivities Mouse
Host Rat
Isotype IgG2b
Clonality Monoclonal
Immunogen IL-4 producing Th2 cell lines including D10
Specificity This antibody is specific to CD3e (Mr. 25 kD).
Formulation PBS containing 0.09% Sodium Azide as preservative
Label: FITC
State: Liquid purified Ig fraction
Label: Fluorescein Isothiocyanate Isomer 1
Concentration 0.5 mg/ml
Conjugation FITC
Background CD3e, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chain ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. (Ref.1,2)
CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation.
The monoclonal antibody C363.29B recognizes an epitope on the 25kD epsilon chain of the CD3/TCR complex. (Ref.1) In the presence of Fc receptor-bearing accessory cells, soluble C363.29B can activate primed and naïve T cell in vitro. Immobilized C363.29 monoclonal antibody can also activate both normal T lymphocytes and cloned T cell lines provided the appropriate accessory signals are present. (Ref.1,3,4)
The monoclonal antibody is cytolytic, easily used for cell surface staining and a good immunoprecipitating antibody. (Ref.1)
Synonyms T3/Leu-4
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.