Cd3e Rat Monoclonal Antibody [Clone ID: C363.29B (YCD3-1)]

CAT#: AM08026LE-N

Cd3e rat monoclonal antibody, clone C363.29B (YCD3-1), Low Endotoxin


USD 320.00

3 Days*

Size
    • 500 ug

Product Images

Specifications

Product Data
Clone Name C363.29B (YCD3-1)
Applications FC, FN
Recommended Dilution Flow Cytometry: Identification and enumeration of CD3+. (Ref.1,2).
Functional Assay:
In vitro Depletion of CD3+ cells. (Ref.1)
In vitro Activation of T cells (accessory cells must be provided). (Ref.1,3,4)
Reactivities Mouse
Host Rat
Isotype IgG2b
Clonality Monoclonal
Specificity This Low Endotoxin/Azide free antibody is specific to CD3e (Mr. 25 kD).
The monoclonal antibody C363.29B recognizes an epitope on the 25kD epsilon chain of the CD3/TCR complex. (Ref.1) In the presence of Fc receptor-bearing accessory cells, soluble C363.29B can activate primed and naïve T cell in vitro.
Immobilized C363.29 monoclonal antibody can also activate both normal T lymphocytes and cloned T cell lines provided the appropriate accessory signals are present. (Ref.1,3,4) The monoclonal antibody is cytolytic, easily used for cell surface staining and a good immunoprecipitating antibody. (Ref.1)
Formulation PBS without preservatives.
State: Low Endotoxin
State: Liquid purified Ig fraction.
Concentration 0.5 mg/ml
Background CD3e, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chain ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. (Ref.1,2)
CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation.
Synonyms T3/Leu-4
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.