Cd24a Rat Monoclonal Antibody [Clone ID: 91]

CAT#: AM08034FC-N

Cd24a rat monoclonal antibody, clone 91, FITC

Product Images

Immunofluoscent Staining: BALB/c splenocytes were double-stained with Rat anti-Mouse CD24-FITC and Hamster anti-Mouse CD3-RPE (Clone 145-2C11). Small lymphocytes were gated and analyzed on a FACScan (TM) flow cytometer (BDIS, San Jose, CA). Amount Used: 3 ug/10e6 cells.

Specifications

Product Data

• Clone Name: 91
• Applications: FC
• Recommended Dilution: Flow Cytometry: < / = 4 µg/10e6 cells. (Ref.8)
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Specificity: This antibody is specific to Heat Stable Antigen HSA (Mr 35-45 kDa).
• Formulation: PBS containing 0.09% Sodium Azide as preservative.
  Label: FITC
  State: Liquid purified Ig fraction.
  Label: Fluorescein Isothiocyanate Isomer 1
• Concentration: 0.5 mg/ml
• Conjugation: FITC
• Database Link:
  Entrez Gene 12484 Mouse
• Background: CD24, also known as heat stable antigen, is a phosphatidylinositol-linked cell surface glycoprotein that is expressed at all stages of B cell development and on most thymocytes. (Ref.1-3) The absence of expression from mature T cells is closely associated with their maturation from CD4+CD8+CD24+ thymocytes to either CD4+CD8-CD24- or CD4-CD8+CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. (Ref.4-6) Its ligand is P-selectin (CD62P). (Ref.7) CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes. (Ref.1-3).
  The monoclonal antibody 91 can be used to inhibit B-cell differentiation. (Ref.8)
• Synonyms: X62 heat stable antigen, HSA