Cd28 Hamster Monoclonal Antibody [Clone ID: 37.51]

CAT#: AM08037BT-N

Cd28 hamster monoclonal antibody, clone 37.51, Biotin

Specifications

Product Data

• Clone Name: 37.51
• Applications: FC
• Recommended Dilution: Flow Cytometry: < / = 2 µg/10e6 cells. (Ref.2-5)
• Reactivities: Mouse
• Host: Hamster
• Isotype: IgG
• Clonality: Monoclonal
• Specificity: This antibody is specific to CD28 costimulatory receptor (Mr. 40 kDa)
• Formulation: PBS containing 0.09% Sodium Azide as preservative.
  Label: Biotin
  State: Liquid purified Ig fraction.
• Concentration: 0.5 mg/ml
• Conjugation: Biotin
• Gene Name: CD28 antigen
• Database Link:
  Entrez Gene 12487 Mouse
• Background: CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. (Ref.1-4)
  CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses. (Ref.5-8)
• Synonyms: TP44