Tnfrsf8 Hamster Monoclonal Antibody [Clone ID: mCD30.1]

CAT#: AM08039LE-N

Tnfrsf8 hamster monoclonal antibody, clone mCD30.1, Low Endotoxin


USD 440.00

3 Days*

Size
    • 500 ug

Product Images

Specifications

Product Data
Clone Name mCD30.1
Applications FC, FN
Recommended Dilution Flow Cytometry. (Ref.1)
Functional Assay: In vitro costimulation of T cells and NK cells. (Ref.1)
Reactivities Mouse
Host Hamster
Isotype IgG
Clonality Monoclonal
Immunogen Recombinant mouse CD30 extracellular domain-mouse IgG1 fusion protein. (Ref.1)
Specificity This antibody is specific to Murine CD30, Mr 52 kDa (core peptide).
Formulation PBS containing no preservatives.
State: Low Endotoxin
State: Liquid purified Ig fraction.
Concentration 0.5 mg/ml
Background CD30 is a type I transmembrane protein and a member of the tumor necrosis factor receptor superfamily of proteins. (Ref.1,2) Murine CD30 is expressed predominantly in the thymus, and it is inducible in mouse splenocytes stimulated with pokeweed mitogen or concanavalin A. (Ref.1) In anti-CD3e-activated spleen cells, CD30 is expressed primarily on the surface of CD8+ T cells with peak expression on days 4 and 5. Stimulation of CD30+ CTL lines with plate-bound anti-CD30 directly signals IL-5 but not IFN-gamma production. (Ref.1)
While these studies demonstrate that CD30 directs cytokine secretion and suggest that CD30 may play a pivotal role in the pattern of cytokine production by T cells, the precise roles of CD30 and its ligand (CD153) in T-cell development have not been clearly defined.
Synonyms TNFRSF8, D1S166E, CD30L receptor, KI-1 antigen
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.