Cd38 Rat Monoclonal Antibody [Clone ID: NIMR-5]

CAT#: AM08041FC-N

Cd38 rat monoclonal antibody, clone NIMR-5, FITC


USD 420.00

3 Days*

Size
    • 500 ug

Product Images

Specifications

Product Data
Clone Name NIMR-5
Applications FC
Recommended Dilution Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1-8)
Reactivities Mouse
Host Rat
Isotype IgG2a
Clonality Monoclonal
Specificity This antibody is specific to CD38 (Mr. 42-46 kDa).
Monoclonal antibodies to CD38 have been shown to induce B- and T-cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis. (Ref.1-8)
Formulation PBS containing 0.09% Sodium Azide as preservative.
Label: FITC
State: Liquid purified Ig fraction.
Label: Fluorescein Isothiocyanate Isomer 1
Concentration 0.5 mg/ml
Conjugation FITC
Background Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing Nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells, and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCRalphabeta+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages.
Synonyms cADPr hydrolase 1, T10
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.