Cd72 (CD72.1 alloantigen) Mouse Monoclonal Antibody [Clone ID: 10-1.D.2]

CAT#: AM08051RP-N

Cd72 (CD72.1 alloantigen) mouse monoclonal antibody, clone 10-1.D.2, PE


USD 230.00

3 Days*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name 10-1.D.2
Applications FC
Recommended Dilution Flow Cytometry: < / = 0.2 µg/10e6 cells. (Ref.1,2)
Reactivities Mouse
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen DBA/2 mouse spleen cells. (Ref.1)
Specificity This antibody recognises CD72.1/Lyb-2.1 (Mr. 45 kDa).
Formulation PBS containing 0.09% Sodium Azide as preservative and a stabilizing agent.
Label: PE
State: Liquid purified Ig fraction.
Label: R-Phycoerythrin
Concentration 0.1 mg/ml
Conjugation PE
Gene Name CD72 antigen
Background Murine CD72.1/Lyb-2.1, a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells, and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 (Ly-1) which is distributed on all T cells and a small number of B cells. (Ref.1,2)
This clone blocks binding of CD5 to CD72 on the B cell surface, which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. (Ref.1) However, 10-1.D.2 can itself trigger a positive signal by binding CD72. (Ref.1-5)
Synonyms Lyb-2, Ly-32, Ly32, B-Cell marker
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.