Thy1 Rat Monoclonal Antibody [Clone ID: G7]

CAT#: AM08054FC-N

Thy1 rat monoclonal antibody, clone G7, FITC


USD 380.00

3 Days*

Size
    • 500 ug

Product Images

Specifications

Product Data
Clone Name G7
Applications FC
Recommended Dilution Flow Cytometry: ≤ 1 µg/106 cells. (Ref.1, 6-8)
Reactivities Mouse
Host Rat
Isotype IgG2c
Clonality Monoclonal
Immunogen Mouse T cell hybridoma C6/G8
Specificity This antibody recognises Thy-1.1 and Thy-1.2 alloantigens (Thy-1 epitope region A), Mr 28-32 kDa.
Formulation PBS containing 0.09% Sodium Azide as preservative.
Label: FITC
State: Liquid purified Ig fraction.
Label: Fluorescein Isothiocyanate Isomer 1
Concentration 0.5 mg/ml
Conjugation FITC
Background CD90/Thy-1, a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily of cell surface receptors, consists of a single V-set domain. (Ref.1-4) It is expressed on thymocytes, peripheral T lymphocytes, some intraepithelial T lymphocytes and neurons of all mouse strains. (Ref.1,2) MAb G7 stimulates T-cell proliferation and IL-2 secretion, via signalling through the T-cell receptor/CD3 complex. (Ref.1,5-7). It has also been reported to promote apoptosis of thymocytes and CTL clones (Ref.4,7) and to mediate adhesion of thymocytes to thymic stroma. (Ref.8)
Synonyms Thy-1, THY1, CDw90
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.