Ctla4 Hamster Monoclonal Antibody [Clone ID: 1B8]

CAT#: AM08060BT-N

Ctla4 hamster monoclonal antibody, clone 1B8, Biotin

Specifications

Product Data

• Clone Name: 1B8
• Applications: FC
• Recommended Dilution: Flow Cytometry: < / = 3 µg/10e6 cells. (Ref.1,2)
• Reactivities: Mouse
• Host: Hamster
• Isotype: IgG
• Clonality: Monoclonal
• Specificity: This Monoclonal antibody is specific to CD152/CTLA-4.
• Formulation: PBS containing 0.09% Sodium Azide as preservative.
  Label: Biotin
  State: Liquid purified Ig fraction.
• Concentration: 0.5 mg/ml
• Conjugation: Biotin
• Database Link:
  Entrez Gene 12477 Mouse
• Background: The lymphocyte surface antigen CD152, also known as CTLA-4, is related to the co-stimulatory molecule CD28, and both molecules share common B7 family counter-receptors. (Ref.1-4) However CD152 is thought to be a negative regulator of T cell activation (Ref.1-3) and may play a role in apoptotic control of T cells. CD152 exists as a 69 kDa homodimer (Ref.1), and is relatively conserved among Humans, Mice and Chickens. (Ref.2)
• Synonyms: CTLA-4