Ly49I Mouse Monoclonal Antibody [Clone ID: YLI-90]

CAT#: AM08065FC-N

Ly49I mouse monoclonal antibody, clone YLI-90, FITC

Specifications

Product Data

• Clone Name: YLI-90
• Applications: FC
• Recommended Dilution: Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1,3)
• Reactivities: Mouse
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Specificity: This antibody react with the B6 allele of the Ly49I.
  It stains ~ 45% of NK1.1+CD3- splenocytes from C57BL/6 mice. (Ref.1)
• Formulation: PBS containing 0.09% Sodium Azide as preservative.
  Label: FITC
  State: Liquid purified Ig fraction.
  Label: Fluorescein Isothiocyanate Isomer 1
• Concentration: 0.5 mg/ml
• Conjugation: FITC
• Background: Ly49I is a member of the lectin like homodimeric Ly49 family of cell surface receptors. (Ref.1) Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down regulated. (Ref.2) These inhibitory receptors are also expressed on a subpopulation of mouse CD8+ T cells.
• Synonyms: Klra9, Ly-49I