Cd24a Rat Monoclonal Antibody [Clone ID: 30-F1]
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Specifications
Product Data | |
Clone Name | 30-F1 |
Applications | FC |
Recommended Dilution | Flow Cytometry (< / = 0.2 µg/10e6 cells) and Cell Sorting. (Ref.3,4,7-10) |
Reactivities | Mouse |
Host | Rat |
Isotype | IgG2c |
Clonality | Monoclonal |
Specificity | This antibody recognises CD24/Heat Stable Antigen (HSA). |
Formulation | PBS containing 0.09% Sodium Azide as preservative and a stabilizing agent. Label: PE State: Liquid purified Ig fraction. Label: R-Phycoerythrin |
Concentration | 0.1 mg/ml |
Conjugation | PE |
Database Link | |
Background | CD24 (also known as heat stable antigen) is a phosphatidylinositol linked cell surface glycoprotein with a polypeptide core of 30 amino acids and high carbohydrate content. The apparent molecular mass of the two forms of CD24 purified from a mouse lymphoma cell line appear to be in the range of 40-60 and 23-30 kDa. CD24 is expressed at all stages of B cell development and on most thymocytes. The absence of expression from mature T cells is closely associated with their maturation from CD4+ CD8+ CD24+ thymocytes to either CD4+ CD8- CD24- or CD4- CD8+ CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. Its ligand is P selectin (CD62P). CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes. CD24 is also a positive marker of pancreatic cancer. |
Synonyms | X62 heat stable antigen, HSA |
Reference Data |
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