CD81 / TAPA1 Hamster Monoclonal Antibody [Clone ID: 2F7]

CAT#: AM08071LE-N

CD81 / TAPA1 hamster monoclonal antibody, clone 2F7, Low Endotoxin


USD 400.00

3 Days*

Size
    • 500 ug

Product Images

Specifications

Product Data
Clone Name 2F7
Applications FC, FN, IHC, IP
Recommended Dilution Flow Cytometry: Identification and enumeration of CD81+ cells.
Immunoprecipitation.
Immunohistochemistry on Frozen Sections.
In vitro blocking of thymocyte interactions with CD81.
See Ref.2 for more details.
Reactivities Mouse
Host Hamster
Isotype IgG
Clonality Monoclonal
Immunogen Mouse epithelial cell line PAM212.
Specificity This antibody recognises Mouse CD81 (Mr 25 kDa), a member of the transmembrane 4 integral membrane protein
family. This antibody can block thymocyte interaction with CD81 in vitro. (Ref.2)
Formulation PBS without preservatives.
State: Low Endotoxin
State: Liquid purified Ig fraction.
Concentration 0.5 mg/ml
Background TAPA1, or CD81, is a member of the transmembrane 4 superfamily, also known as the Tetraspanin family. Most of these members are cell surface proteins that are characterised by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TAPA1 is a cell surface glycoprotein that is known to complex with integrins. It appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. TAPA1 gene is localized in the tumor suppressor gene region and thus it is a candidate gene for malignancies.
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.