Cd79b Hamster Monoclonal Antibody [Clone ID: HM79-12]

CAT#: AM08072BT-N

Cd79b hamster monoclonal antibody, clone HM79-12, Biotin

Specifications

Product Data

• Clone Name: HM79-12
• Applications: FC
• Recommended Dilution: Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1,2)
• Reactivities: Mouse
• Host: Hamster
• Isotype: IgG
• Clonality: Monoclonal
• Specificity: This antibody recognises beta chain of the mouse B-cell receptor (Mr. 23 kDa).
• Formulation: PBS containing 0.09% Sodium Azide as preservative.
  Label: Biotin
  State: Liquid purified Ig fraction.
• Concentration: 0.5 mg/ml
• Conjugation: Biotin
• Database Link:
  Entrez Gene 15985 Mouse
• Background: Murine CD79 is a 23/21 kDa disulfide-linked heterodimer composed of an alpha chain (CD79a/mb-1) and a beta chain (CD79b/B29) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes, first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation. (Ref.1)
• Synonyms: B29, IGB, B-Cell marker