MHC Class II I-Ab Mouse Monoclonal Antibody [Clone ID: 25-9-3]

CAT#: AM08076RP-N

MHC Class II I-Ab mouse monoclonal antibody, clone 25-9-3, PE


USD 340.00

3 Days*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name 25-9-3
Applications FC
Recommended Dilution Flow Cytometry: < / = 0.2 µg/10e6 cells.
Reactivities Mouse
Host Mouse
Isotype IgM
Clonality Monoclonal
Immunogen C3H.SW splenocytes. (Ref.1)
Specificity This antibody reacts specifically with the I-Ab haplotype of MHC Class II molecules.
Class II antigens are predominantly expressed on antigen-presenting cells including B lymphocytes, macrophages, dendritic cells and certain epithelial cells.
Formulation PBS containing 0.09% Sodium Azide as preservative and a stabilizing agent.
Label: PE
State: Liquid purified Ig fraction.
Label: R-Phycoerythrin
Concentration 0.1 mg/ml
Conjugation PE
Background MHC Class II antigens are involved in antigen presentation by Antigen Presenting Cells (APCs) to CD4+ T cells. They are constitutively expressed on APCs including B cells, macrophages, monocytes and dendritic cells, and are inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma. The Mouse H2 Ab locus is orthologous to human DQB, which varies from typical class II genes in that both the alpha and beta chains are polymorphic.
Synonyms H2-Eb1, H-2 class II histocompatibility antigen I-A beta chain
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.