MHC Class I H-2 Kk Mouse Monoclonal Antibody [Clone ID: 36-7-5]
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Specifications
Product Data | |
Clone Name | 36-7-5 |
Applications | FC |
Recommended Dilution | Flow Cytometry: < / = 0.2 µg/10e6 cells. (Ref.1) |
Reactivities | Mouse |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | A.AL mouse splenocytes. |
Specificity | This antibody reacts with the H-2Kk MHC class I alloantigen. Cross-reactivity with splenocytes of SJL/Hsd mice has been observed by flow cytometric analysis. (Ref.2) It does not react with other (e.g., b, d, q) haplotypes. |
Formulation | PBS containing 0.09% Sodium Azide as preservative and a stabilizing agent Label: PE State: Liquid purified Ig fraction. Label: R-Phycoerythrin |
Concentration | 0.1 mg/ml |
Conjugation | PE |
Background | MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta2- microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. Lymphocytes are highly positive whereas fibroblasts or neurons show only a low level of antigen. |
Synonyms | H2-K1, H2-K, H-2K(K) |
Reference Data |
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