Icam2 Rat Monoclonal Antibody [Clone ID: 3C4]

CAT#: AM08089PU-N

Icam2 rat monoclonal antibody, clone 3C4, Purified

Specifications

Product Data

• Clone Name: 3C4
• Applications: FC, FN, IHC, IP
• Recommended Dilution: Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1,2)
  Immunohistochemistry on Frozen Sections. (Ref.3)
  Immunoprecipitation. (Ref.1)
  In vitro blocking assays. (Ref.1)
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: COS cells transfected with mouse ICAM-2 cDNA. (Ref.1)
• Specificity: This antibody is specific to ICAM-2 (CD102).
  It blocks the interaction between ICAM-2 and LFA-1. (Ref.1)
• Formulation: 100 mM Borate Buffered Saline, pH 8.2.
  No preservatives or amine-containing buffer salts added.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: 0.5 mg/ml
• Database Link:
  Entrez Gene 15896 Mouse
• Background: ICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin like C2 type domains, and bind to the leukocyte adhesion LFA1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA1 dependent cell adhesion. It mediates adhesive interactions important for antigen specific immune response, NK cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
• Synonyms: ICAM-2