RLA-DQ Mouse Monoclonal Antibody [Clone ID: 2C4]
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Specifications
Product Data | |
Clone Name | 2C4 |
Applications | FC |
Recommended Dilution | Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1,3) |
Reactivities | Rabbit |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Specificity | This antibody is specific to Rabbit RLA-DQ alpha chain (Mr ~35 kDa). It reacts with RLA-DQ-transfected cells, but not with RLA-DR-transfected cells. (Ref.2) In normal adult rabbits, the antibody reacts with 30-60% of peripheral blood leukocytes. (Ref.2,3) It has also been reported that the antibody stains: lymphocytes and macrophages in the spleen; lymphocytes in the thymic medulla and some cells in the cortex; Kupffer cells in the liver; and synovial lining cells (i.e., infiltrating macrophages) in inflamed synovium. (Ref.4) DQ alpha transcripts have been detected in bone marrow and spleen and, to a lesser extent, in appendix, lymph nodes, and other organs. (Ref.5) |
Formulation | PBS containing 0.09% Sodium Azide as preservative. Label: Biotin State: Liquid purified Ig fraction. |
Concentration | 0.5 mg/ml |
Conjugation | Biotin |
Synonyms | MHC Class II RLA-DQ |
Reference Data |
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