RLA-DQ Mouse Monoclonal Antibody [Clone ID: 2C4]

CAT#: AM08101FC-N

RLA-DQ mouse monoclonal antibody, clone 2C4, FITC

Specifications

Product Data

• Clone Name: 2C4
• Applications: FC
• Recommended Dilution: Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1,3)
• Reactivities: Rabbit
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Rabbit spleen cells.
• Specificity: This antibody is specific to Rabbit RLA-DQ alpha chain (Mr ~35 kDa).
  It reacts with RLA-DQ-transfected cells, but not with RLA-DR-transfected cells. (Ref.2) In normal adult rabbits, the antibody reacts with 30-60% of peripheral blood leukocytes. (Ref.2,3)
  It has also been reported that the antibody stains: lymphocytes and macrophages in the spleen; lymphocytes in the thymic medulla and some cells in the cortex; Kupffer cells in the liver; and synovial lining cells (i.e., infiltrating macrophages) in inflamed synovium. (Ref.4)
  DQ alpha transcripts have been detected in bone marrow and spleen and, to a lesser extent, in appendix, lymph nodes, and other organs. (Ref.5)
• Formulation: PBS containing 0.09% Sodium Azide as preservative.
  Label: FITC
  State: Liquid purified Ig fraction.
  Label: Fluorescein Isothiocyanate Isomer 1
• Concentration: 0.5 mg/ml
• Conjugation: FITC
• Synonyms: MHC Class II RLA-DQ