CD3E Mouse Monoclonal Antibody [Clone ID: BB23-8E6]
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Specifications
Product Data | |
Clone Name | BB23-8E6 |
Applications | FC |
Recommended Dilution | Flow Cytometry: < / = 0.2 µg/10e6 cells. (Ref.1) |
Reactivities | Porcine |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Specificity | This antibody recognizes Porcine CD3e (Mr. 20 kDa). The Monoclonal antibody BB23-8E6 is Mitogenic when presented to peripheral blood mononuclear cells in immobilized form. (Ref.1) |
Formulation | PBS containing 0.09% Sodium Azide as preservative and a stabilizing agent. Label: PE State: Liquid purified Ig fraction. Label: R-Phycoerythrin |
Concentration | 0.1 mg/ml |
Conjugation | PE |
Gene Name | - |
Background | CD3 epsilon, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains (designated as gamma, delta, epsilon, zeta and eta) ranging in size from 16-28 kDa. CD3 epsilon is closely associated with the T cell antigen receptor (TCR), and is present on thymocytes, CD8+ and CD4+ positive cells. The CD3 epsilon complex mediates signal transduction. It plays a major role in signaling during antigen recognition, leading to T cell activation. The TCR/CD3E complex of T lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. CD3 epsilon is expressed on all T cells of all mouse strains. |
Synonyms | T3/Leu-4 |
Reference Data |
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