CD21 (CR2) Mouse Monoclonal Antibody [Clone ID: BB6-11C9.6]

CAT#: AM08109PU-N

CD21 (CR2) mouse monoclonal antibody, clone BB6-11C9.6, Purified


USD 490.00

3 Days*

Size
    • 500 ug

Product Images

Specifications

Product Data
Clone Name BB6-11C9.6
Applications FC, IHC, IP
Recommended Dilution Flow Cytometry. (Ref.2-3)
Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections only). (Ref.2)
Immunoprecipitation. (Ref.2)
Reactivities Porcine
Host Mouse
Isotype IgG1
Clonality Monoclonal
Specificity This antibody is specific to Porcine CD21 (Mr. 160 kDa).
It stains the following percentages of surface immunoglobulin (sIg) positive cells in porcine lymphoid tissues: 92-96% in peripheral blood; 74-98% in mesenteric lymph nodes; 97-100% in ileal Peyer’s patches (ILPP); 93-97% in spleen; and 0% in thymus. The antibody does not stain B cells in cord blood or spleen from pig fetuses (105 days gestation). Does not stain B cells in cord blood or spleen from pig fetuses (105 days gestation).
Formulation 100 mM Borate Buffered Saline, pH 8.2.
No preservatives or amine-containing buffer salts added.
State: Purified
State: Liquid purified Ig fraction.
Concentration lot specific
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens complement component 3d receptor 2 (CR2), transcript variant 1
Background CD21 also known as complement receptor 2 (CR2), C3d receptor or EBV receptor is a 140 kDa protein. CD21 is a glycosylated type I transmembrane protein consisting of an extracellular face of a series of 15 or 16 CCP domains. CD21 is the receptor for complement components C3d and iC3b as well as the Epstein-Barr virus (EBV) glycoprotein gp350/220. The soluble CD21 (sCD21) was shown to efficiently trigger CD23 signalling pathways in human monocytes. By inducing release of proinflammatory cytokines and upregulating expression of molecules involved in antigen presentation, sCD21 modulates critical monocyte functions that may be relevant to allergic and inflammatory disorders.
Synonyms Complement receptor type 2, CR2, C3DR, C3d receptor, EBV Receptor, Dendritic Cell Marker
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways B cell receptor signaling pathway, Complement and coagulation cascades, Hematopoietic cell lineage

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.