B-Cells (subset) Mouse Monoclonal Antibody [Clone ID: BB6-10A10]
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Specifications
Product Data | |
Clone Name | BB6-10A10 |
Applications | FC |
Recommended Dilution | Flow Cytometry: < / = 0.2 µg/10e6 cells. (Ref.1-2) |
Reactivities | Porcine |
Host | Mouse |
Isotype | IgM |
Clonality | Monoclonal |
Specificity | This antibody stains the following percentages of surface immunoglobulin (sIg) positive cells in porcine lymphoid tissues: 11-15% in peripheral blood; 22-23% in mesenteric lymph nodes; 79-87% in ileal Peyer's patches (ILPP); 6-17 in spleen; and 0% in thymus (Ref.1). While identification of the antigen(s) that are found predominantly on ILPP B cells and which are recognized by BB6-10A10 is speculative, the antibody appears to react with an immature population of B cells in the follicles of ILPPs and with a subpopulation of sIglow B cells in lymph nodes. |
Formulation | PBS containing 0.09% Sodium Azide as preservative and a stabilizing agent. Label: PE State: Liquid purified Ig fraction. Label: R-Phycoerythrin |
Concentration | 0.1 mg/ml |
Conjugation | PE |
Background | B cells are lymphocytes that are produced in the bone marrow and require bone marrow stromal cells and their cytokines for maturation. During its development, each B cell becomes genetically programmed through a series of gene splicing reactions to produce an antibody molecule with a unique specificity. |
Synonyms | B-cell marker, B cells |
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