CD8A Mouse Monoclonal Antibody [Clone ID: fCD8]
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Specifications
Product Data | |
Clone Name | fCD8 |
Applications | FC |
Recommended Dilution | Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1-2) |
Reactivities | Feline |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Specificity | This antibody recognizes Feline CD8 (Mr. 70 kDa) (38/31 kDa under reducing conditions). |
Formulation | PBS containing 0.09% Sodium Azide as preservative. Label: FITC State: Liquid purified Ig fraction. Label: Fluorescein Isothiocyanate Isomer 1 |
Concentration | 0.5 mg/ml |
Conjugation | FITC |
Background | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. |
Synonyms | CD8 alpha chain, CD8A, MAL |
Reference Data |
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