CD8B Mouse Monoclonal Antibody [Clone ID: EP42]

CAT#: AM08123BT-N

CD8B mouse monoclonal antibody, clone EP42, Biotin


USD 450.00

3 Days*

Size
    • 500 ug

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Specifications

Product Data
Clone Name EP42
Applications FC
Recommended Dilution Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.2)
Reactivities Chicken
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Specificity This antibody recognizes beta chain of Chicken CD8 (Mr. 34 kDa).
Formulation PBS containing 0.09% Sodium Azide as preservative.
Label: Biotin
State: Liquid purified Ig fraction.
Concentration 0.5 mg/ml
Conjugation Biotin
Background The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Chicken CD8 is expressed on approximately 80% of thymocytes, 45% of blood mononuclear cells and 50% of spleen cells, but <1% of cells in the bursa and bone marrow. (Ref.1,2)
Synonyms CD8B, CD8B1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.