CD8B Mouse Monoclonal Antibody [Clone ID: EP42]

CAT#: AM08123PU-N

CD8B mouse monoclonal antibody, clone EP42, Purified

Specifications

Product Data

• Clone Name: EP42
• Applications: FC, IHC, IP
• Recommended Dilution: Flow Cytometry. (Ref.2)
  Immunoprecipitation. (Ref.2)
  Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections. (Ref.4)
• Reactivities: Chicken
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Specificity: This antibody recognizes beta chain of Chicken CD8 (Mr. 34 kDa).
• Formulation: 100 mM Borate Buffered Saline, pH 8.2.
  No preservatives or amine-containing buffer salts added.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: 0.5 mg/ml
• Database Link:
  Entrez Gene 396175 Chicken
• Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
  Chicken CD8 is expressed on approximately 80% of thymocytes, 45% of blood mononuclear cells and 50% of spleen cells, but <1% of cells in the bursa and bone marrow. (Ref.1,2)
• Synonyms: CD8B, CD8B1