MHC Class I Mouse Monoclonal Antibody [Clone ID: F21-2]

CAT#: AM08130FC-N

MHC Class I mouse monoclonal antibody, clone F21-2, FITC


USD 500.00

3 Days*

Size
    • 500 ug

Product Images

Specifications

Product Data
Clone Name F21-2
Applications FC
Recommended Dilution Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1-4)
Reactivities Chicken
Host Mouse
Isotype IgG1
Clonality Monoclonal
Specificity This antibody recognizes a monomorphic epitope on avian MHC Class I molecules (Mr ~ 68 kDa). It also reacts with Turkey MHC Class I.
Formulation PBS containing 0.09% Sodium Azide as preservative.
Label: FITC
State: Liquid purified Ig fraction.
Label: Fluorescein Isothiocyanate Isomer 1
Concentration 0.5 mg/ml
Conjugation FITC
Background MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. (Ref.1-3) Fibroblasts or neurons however only show a low level of antigen.
Synonyms MHC Class 1, HLA Class 1
Reference Data

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.