KIT Mouse Monoclonal Antibody [Clone ID: kit2c75]

CAT#: AM08136FC-N

KIT mouse monoclonal antibody, clone kit2c75, FITC


USD 500.00

3 Days*

Size
    • 500 ug

Product Images

Specifications

Product Data
Clone Name kit2c75
Applications FC
Recommended Dilution Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.6-10)
Reactivities Chicken
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Sp2/0 cells, Sp/chkit4A4, transfected with Chicken c-kit cDNA.
Specificity This antibody recognizes Chicken c-Kit.
Formulation PBS containing 0.09% Sodium Azide as preservative.
Label: FITC
State: Liquid purified Ig fraction.
Label: Fluorescein Isothiocyanate Isomer 1
Concentration 0.5 mg/ml
Conjugation FITC
Gene Name v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Background c-Kit is a transmembrane tyrosine kinase encoded by the cKit proto oncogene. c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, and activation. Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, gastrointestinal stromal tumor, acute myeloid leukemia, Ewing sarcoma and lung cancer. Phosphorylation at tyrosine 721 of c-Kit allows binding and activation of PI3 kinase.
Synonyms SCFR, KIT
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.