CD44 Mouse Monoclonal Antibody [Clone ID: AV6]
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Specifications
Product Data | |
Clone Name | AV6 |
Applications | FC |
Recommended Dilution | Flow Cytometry: < / = 1 µg/10e6 cells. |
Reactivities | Chicken |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Specificity | This antibody is specific to Chicken CD44 (Mr 90 kDa). It also reacts with IgM+ Turkey B cells and a subset of Turkey lymphocytes. |
Formulation | PBS containing 0.09% Sodium Azide as preservative. Label: FITC State: Liquid purified Ig fraction. Label: Fluorescein Isothiocyanate Isomer 1 |
Concentration | 0.5 mg/ml |
Conjugation | FITC |
Background | CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix. |
Synonyms | LHR, MDU2, MDU3, MIC4, CDw44, Epican, ECMR-III, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, PGP-1 |
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