CD20 (MS4A1) F(ab)2 Fragment Mouse Monoclonal Antibody [Clone ID: B-Ly1]
CAT#: AM08155PU-N
CD20 (MS4A1) F(ab)2 Fragment mouse monoclonal antibody, clone B-Ly1, Purified
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Specifications
Product Data | |
Clone Name | B-Ly1 |
Applications | FC, IHC |
Recommended Dilution | Flow Cytometry. Immunohistochemistry on Frozen Sections. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Unknown. |
Specificity | This antibody recognizes CD20. |
Formulation | 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Storage | Store the antibody undiluted at 2-8°C. |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | CD20 is a non glycosylated protein with a molecular weight of 33 - 37 kDa depending on the degree of phosphorylation. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit. (Ref-1-4) |
Synonyms | MS4A1, Leu-16, Bp35, B-cell marker |
Reference Data |
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