CD4 Mouse Monoclonal Antibody [Clone ID: RFT-4g]
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Specifications
Product Data | |
Clone Name | RFT-4g |
Applications | FC, IHC, IP |
Recommended Dilution | Flow Cytometry. Immunohistochemistry on Frozen Sections. Immunoprecipitation. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Specificity | This antibody recognizes CD4. |
Formulation | PBS without preservatives. State: Low Endotoxin State: Liquid purified Ig fraction. |
Concentration | 0.5 mg/ml |
Database Link | |
Background | CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase. CD4 functions as an accessary molecule in the recognition of foreign antigens in association with MHC Class II antigens by T cells. (Ref.1-6) |
Synonyms | T-cell surface antigen T4/Leu-3 |
Reference Data |
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