CD8A Mouse Monoclonal Antibody [Clone ID: RFT-8]

CAT#: AM08158RC5-N

CD8A mouse monoclonal antibody, clone RFT-8, PE-Cy5.5


USD 360.00

3 Days*

Size
    • 100 Tests

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Specifications

Product Data
Clone Name RFT-8
Applications FC, IHC
Recommended Dilution Flow Cytometry: 10 µL/10e6 cells.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Specificity This antibody recognizes CD8.
Formulation PBS containing 0.09% Sodium Azide as preservative and a stabilizing agent.
Label: PE-Cy5.5
State: Liquid purified Ig fraction.
Label: R-Phycoerythrin-Cyanine 5.5
Conjugation PE-Cy5.5
Storage Store the antibody undiluted at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens CD8a molecule (CD8A), transcript variant 1
Background The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8 functions primarily as a coreceptor with MHC Class I-restricted TCR's in antigen recognition. (Ref.1-2)
Synonyms CD8 alpha chain, CD8A, MAL
Reference Data
Protein Families Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane
Protein Pathways Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.