CD16 (FCGR3A) Mouse Monoclonal Antibody [Clone ID: GRM1]

CAT#: AM08159FC-N

CD16 (FCGR3A) mouse monoclonal antibody, clone GRM1, FITC


USD 310.00

3 Days*

Size
    • 100 Tests

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Specifications

Product Data
Clone Name GRM1
Applications FC
Recommended Dilution Flow Cytometry: 10 µL/10e6 cells.
Reactivities Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Specificity This antibody recognizes CD16/FcgammaRIII.
Formulation PBS containing 0.09% Sodium Azide as preservative.
Label: FITC
State: Liquid purified Ig fraction.
Label: Fluorescein Isothiocyanate Isomer 1
Conjugation FITC
Storage Store the antibody undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer.
This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens Fc fragment of IgG receptor IIIa (FCGR3A), transcript variant 1
Background CD16 (FcgammaRIII) serves as a low affinity IgG receptor. Human CD16 is expressed in two forms CD16a and CD16b. CD16a is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. CD16b is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.
CD16 is involved in NK activation and signal transduction. (Ref.1-5)
Synonyms FCGR3A, CD16A, FCG3, FCGR3, IGFR3, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcR-10, IgG Fc receptor III-2
Reference Data
Protein Families ES Cell Differentiation/IPS, Secreted Protein, Transmembrane
Protein Pathways Fc gamma R-mediated phagocytosis, Natural killer cell mediated cytotoxicity, Systemic lupus erythematosus

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.