LOC105369261 Mouse Monoclonal Antibody [Clone ID: DF-T1]

CAT#: AM08160SU-N

LOC105369261 mouse monoclonal antibody, clone DF-T1, Supernatant

Product Images

Formalin-Fixed, Paraffin-Embedded Human lymph node stained with CD43 antibody Cat.-No. AM08160SU-N using peroxidase conjugate and DAB chromogen. Note the cell membrane staining of perifollicular T-cells.

Specifications

Product Data

• Clone Name: DF-T1
• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Sections: 1/100
  Pretreatment of deperaffinized tissue with heat-induced epitope retrieval is recommended.
  Use Polymer anti Mouse/Rabbit IgG as a detection system.
  Positive Control: Tonsil, CLL/SLL, or lymph node.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Stimulated Human leukocytes.
• Specificity: Recognizes CD43.
  Cellular Localization: Cell membrane.
• Formulation: State: Supernatant
  State: Tissue Culture Supernatant with 0.2% BSA and 15mM Sodium Azide.
• Gene Name: Homo sapiens CD163 molecule (CD163), transcript variant 1
• Database Link:
  Entrez Gene 105369261 Human
• Background: CD43 is a cell surface glycoprotein which is expressed on all thymocytes and T-cells. CD43 is involved in activation of T cells, B cells, NK cells, and monocytes.
  CD43, which is also known as leukosialin, galactoglycoprotein and sialophorin. CD43 is a sialomucin which like many mucins can have both adhesive and anti-adhesive functions. Expression of CD43 is found on most leukocytes except resting B lymphocytes. Proteolytic processing upon activation decreases surface expression. CD43 is involved in activation of T cells, B cells, NK cells, and monocytes. The counter-receptor for CD43 is CD169/SIGLEC-1, which is expressed on macrophages.
• Synonyms: Leukocyte sialoglycoprotein, Sialophorin, Galactoglycoprotein, SPN

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane