CD55 / DAF Mouse Monoclonal Antibody [Clone ID: 143-30]
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Specifications
Product Data | |
Clone Name | 143-30 |
Applications | FC |
Recommended Dilution | Flow Cytometry: 10 µL/10e6 cells. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Specificity | This antibody recognizes CD55. |
Formulation | PBS containing 0.09% Sodium Azide as preservative and a stabilizing agent. Label: PE State: Liquid purified Ig fraction. Label: R-Phycoerythrin |
Conjugation | PE |
Background | CD55, also known as decay accelerating factor (DAF), is a 64-73 kDa GPI-anchored single chain glycoprotein that is expressed on all cells in contact with serum, including all hematopoietic cells and the vascular endothelium. A soluble form of CD55 is present in plasma and body fluids. CD55 is a member of the regulator of complement activity (RCA) family of proteins and is thought to play a role in the protection of cells from damage by autologous complement by preventing the amplification steps of the complement cascade. CD55 expression increases upon T cell activation and antibodies to CD55 are mitogenic in the presence of phorbol esters. (Ref.1-5) |
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