CD71 (TFRC) Mouse Monoclonal Antibody [Clone ID: RVS10]

CAT#: AM08163AC-N

CD71 (TFRC) mouse monoclonal antibody, clone RVS10, APC


USD 300.00

3 Days*

Size
    • 100 Tests

Product Images

Specifications

Product Data
Clone Name RVS10
Applications FC
Recommended Dilution Flow Cytometry: 10 µL/10e6 cells.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Specificity This antibody is directed against the Human Transferrin Receptor (CD71).
Formulation PBS containing 0.09% Sodium Azide as preservative and a stabilizing agent.
Label: APC
State: Liquid purified Ig fraction.
Label: Allophycocyanin
Conjugation APC
Storage Store the antibody undiluted at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name transferrin receptor
Background The Transferrin Receptor has been structurally characterized as a sulfide bound dimer of identical glycoprotein subunits of 95 kDa. The transferrin receptor is not present on resting blood lymphocytes. On PBL, the receptor appears after activation. The expression of transferrin receptor is coordinately regulated with cell growth. Present on T and B cell lines. The soluble (or serum) transferrin receptor (sTfR) is a circulating truncated form of the membrane receptor protein; it is an 85 kDa glycoprotein forming in serum a 320 kDa complex with diferric transferrin. The most important clinical use of the sTfR determination is in the differential diagnosis between iron deficiency anaemia and the anaemia of chronic disease.
CD71 plays a critical role in cell proliferation by controlling the supply of iron, which is essential for many metabolic pathways, through the binding and endocytosis of transferrin. (Ref.1-4)
Synonyms TfR1, p90, Transferrin receptor protein 1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.