CD79B Mouse Monoclonal Antibody [Clone ID: CB3-1]

CAT#: AM08164PU-N

CD79B mouse monoclonal antibody, clone CB3-1, Purified

Specifications

Product Data

• Clone Name: CB3-1
• Applications: FC, IHC, IP
• Recommended Dilution: Flow Cytometry: ? 1 µg/10⁶ cells.
  Immunohistochemistry on Frozen Sections (Reported).
  Immunoprecipitation (Reported in Ref 1,2).
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Ramos B cells.
• Specificity: This antibody reacts with the beta chain of CD79. (Ref.1-4)
• Formulation: 100 mM Borate Buffered Saline, pH 8.2.
  No preservatives or amine-containing buffer salts added.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 974 Human
• Background: CD79 is a 23/21 disulfide-linked heterodimer composed of an alpha chain (CD79a/mb-1) and a beta chain (CD79b/B29).
  CD79b is the B cell antigen receptor Ig beta chain (BCR Ig beta), which associates with B cell antigen receptor Ig alpha chain to form a functional heterodimer that interacts with membrane immunoglobulin (mIg). The mIgM component binds antigen and the Ig alpha/Ig beta heterodimer tranduces signals. CD79 beta is a B cell specific marker, valuable for the detection of B cells at all maturation stages.
• Synonyms: B29, IGB, B-Cell marker