GM CSF (CSF2) Rat Monoclonal Antibody [Clone ID: BVD2-21C11]

CAT#: AM08177BT-N

GM CSF (CSF2) rat monoclonal antibody, clone BVD2-21C11, Biotin


USD 410.00

3 Days*

Size
    • 500 ug

Product Images

Specifications

Product Data
Clone Name BVD2-21C11
Applications ELISA, FC, IF
Recommended Dilution ELISA Detection: Biotinylated Monoclonal antibody AM08177BT-N is the preferred detection antibody in a Sandwich ELISA for quantifying human GM-CSF protein levels. (Ref.1-4). It should be paired with purified with
purified recombinant human GM-CSF as the standard.
Immunofluorescence/Flow Cytometry: This antibody is useful for Intracytoplasmic staining and Flow Cytometric analysis to identify and enumerate GM-CSF-positive cells within mixed cell populations.
Recombinant human GM-CSF (Cat#AM08177PU-N should be used as a Specificity Control.
Reactivities Human
Host Rat
Isotype IgG2a
Clonality Monoclonal
Immunogen E. coli-expressed human GM-CSF.
Specificity This antibody is specific to Human Granulocyte/Macrophage–Colony Stimulating Factor (GM-CSF)1-4. The BVD2-21C11 antibody has been reported to cross react with GM-CSF from Rhesus monkey. (This is a Neutralizing antibody).
Formulation PBS containing 0.09% Sodium Azide as preservative.
Label: Biotin
State: Liquid purified Ig fraction.
Concentration lot specific
Conjugation Biotin
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity.
Synonyms CSF2, GMCSF, Sargramostim, Molgramostin
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.