IL5 Rat Monoclonal Antibody [Clone ID: JES1-5A10]

CAT#: AM08178PU-N

IL5 rat monoclonal antibody, clone JES1-5A10, Purified

Specifications

Product Data

• Clone Name: JES1-5A10
• Applications: ELISA
• Recommended Dilution: ELISA: Useful useful as a Detection/Capture antibody in a Sandwich ELISA for quantifying human IL-5 protein levels. (Ref.1-5)
• Reactivities: Human
• Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: COS-expressed recombinant human IL-5.
• Specificity: This antibody is specific to Human Interleukin-5/IL-5. (Ref.1-4)
• Formulation: 100 mM Borate buffered saline, pH 8.2 without preservatives or amine-containing buffer salts.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 3567 Human
• Background: Human Interleukin 5 (IL5) is a cytokine produced primarily by activated T lymphocytes. It exists as an antiparallel disulfide-linked homodimeric glycoprotein with 115 amino-acid residues in each chain. Known also as EDG (eosinophil differentiating factor), functions predominantly as an eosinophilopoietic factor. Analysis of its crystal structure reveals a novel two-domain structure, with each domain showing significant homology to the cytokine fold in GM-CSF, M-CSF, IL2, IL4 and growth hormone. Human and Mouse IL5 have 70% amino acid sequence homology.
• Synonyms: IL-5, B-cell differentiation factor I, Eosinophil differentiation factor, T-cell replacing factor, TRF