GSK3 alpha (GSK3A) Mouse Monoclonal Antibody [Clone ID: SBGSK3a2]

CAT#: AM08184HR-N

GSK3 alpha (GSK3A) mouse monoclonal antibody, clone SBGSK3a2, HRP


USD 520.00

3 Days*

Size
    • 1 ml

Product Images

Specifications

Product Data
Clone Name SBGSK3a2
Applications WB
Recommended Dilution Western Blot: 1/5000-1/10,000.
Predicted Molecular Weight: 51 kDa.
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Specificity This antibody is specific for GSK3 alpha.
Formulation 50% Glycerol/50% PBS, pH 7.4 without preservatives.
Label: HRP
State: Liquid purified Ig fraction.
Label: Horseradish Peroxidase
Conjugation HRP
Storage Store the antibody undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background Glycogen synthase kinase 3 alpha belongs to the Ser/Thr family of protein kinases, Cdc2/cdkx subfamily; GSK3 subsubfamily. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, myb, and the transcription factor c jun. GSK3 phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK3 and subsequently inhibits GSK3 acutely leading to the stimulation of glycogen synthesis. GSK3 signaling is performed by two isoforms, GSK3 alpha and GSK3 beta. The two isoforms share 97% sequence similarity within their catalytic domains. GSK3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility.
Synonyms Glycogen synthase kinase-3 alpha, GSK3A, GSK-3 alpha, Factor A
Reference Data

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.