YWHAB

CAT#: AM09043PU-N

Mouse Monoclonal Anti-YWHAB Antibody, Purified


USD 340.00

2 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Clone Name J2E9
Applications IHC, WB
Recommended Dilution ELISA, WB
Reactivities Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Recombinant human 14-3-3 beta (1-246 aa) purified from E. coli
Specificity The antibody recognizes human 14-3-3 beta.
Other species not tested.
Formulation PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
Concentration lot specific
Purification Protein-G affinity chromatography
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Predicted Protein Size 27.9 kDa
Gene Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
Background The 14-3-3 family plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, β, ?, ¦Å, ¦Ò, ¦Æ, ¦Ó and ¦Ç that have been identified in mammals. The 14-3-3 beta, a subtype of the 14-3-3 proteins, was found in B Cells, brain and liver etc. This 14-3-3 beta has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery.
Synonyms GW128; HS1; KCIP-1
Reference Data
Protein Families Druggable Genome
Protein Pathways Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.