NFAT2 (NFATC1) Mouse Monoclonal Antibody [Clone ID: AT1C3]

CAT#: AM09061PU-S

NFAT2 (NFATC1) mouse monoclonal antibody, clone AT1C3, Purified


USD 230.00

2 Weeks*

Size
    • 50 ul

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Other products for "NFATC1"

Specifications

Product Data
Clone Name AT1C3
Applications ELISA, FC, IF, IHC, WB
Recommended Dilution ELISA.
Western blot (1/1,000-1/2,000). 
Flow Cytometry. 
Immunofluorescence.
Immunohistochemistry on Paraffin Sections (10 µg/ml).
This NFATC1 antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Reactivities Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Recombinant human NFATc1 (aa 428-716) purified from E. coli
Specificity The antibody recognizes Human NFATc1.
Other species not tested.
Formulation PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein-G affinity chromatography
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens nuclear factor of activated T-cells 1 (NFATC1), transcript variant 1
Background Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (NFATc1) is a component of the nuclear factor of activated T cells DNA-binding transcription complex which consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. This protein plays a main role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription and functions as a major molecular target for the immunosuppressive drugs such as cyclosporine A. NFATc1 is expressed in most human primary lymphocytes and mature human T- and B-cell neoplasms.
Synonyms NF-ATc1, NFATC1, NFATC
Reference Data
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Axon guidance, B cell receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.