HMG1 (HMGB1) Mouse Monoclonal Antibody [Clone ID: J2E1]
Other products for "HMGB1"
Specifications
Product Data | |
Clone Name | J2E1 |
Applications | ELISA, IHC, WB |
Recommended Dilution | ELISA. Western blot (1:500 - 1:2,000), recommended starting dilution is 1:1,000. Immunohistochemistry (1:100 - 1:300), recommended starting dilution is 1:200. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Recombinant human HMGB1 (1-215aa) purified from High Five (Trichoplusia ni) insect cells. |
Specificity | The antibody recognizes human HMGB1. Other species not tested. |
Formulation | PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein-G affinity chromatography |
Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens high mobility group box 1 (HMGB1), transcript variant 2 |
Database Link | |
Background | High mobility group box1 protein (HMGB1) is a very abundant chromatin-binding protein residing in the eukaryotic cell nucleus and acting in the assembly of nucleoprotein complexes. Inside the cell, HMGB1 binds to DNA and has a role in transcriptional regulation. Outside the cell, HMGB1 acts as a cytokine and has activities that resemble those of tumor necrosis factor. |
Synonyms | High mobility group protein 1, HMG1, HMG-1, High mobility group protein B1, HMGB-1, Amphoterin |
Reference Data | |
Protein Families | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
Protein Pathways | Base excision repair |
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