FKBP52 (FKBP4) Mouse Monoclonal Antibody [Clone ID: AT4D3]

CAT#: AM09071PU-N

FKBP52 (FKBP4) mouse monoclonal antibody, clone AT4D3, Purified


USD 340.00

2 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Clone Name AT4D3
Applications ELISA, IHC, WB
Recommended Dilution ELISA.
Western blot (1/1,000-1/2,000). 
Cell lysates of HeLa (40 µg) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human FkBP4 (1/1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. 
Immunohistochemistry on Paraffin Embedded Tissue (1/50-1/100). 
Paraffin embedded sections of Seminoma (Germ cell tumor) tissue were incubated with anti-Human FKBP4 (1/50) for 2 hours at RT. Antigen retrieval was performed in 0.1M sodium citrate buffer and detected using Diaminobenzidine (DAB).
Reactivities Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Recombinant Human FKBP4 (1-459 aa) purified from E. coli
Specificity The antibody recognizes Human FKBP4. Other species not tested.
Formulation PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Affinity Chromatography on Protein G
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens FK506 binding protein 4 (FKBP4)
Background FKBP4, also known as FKBP52, is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. It is a component of unactivated mammalian steroid receptor complexes and may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes.
Synonyms FK506-binding protein 4, FKBP52 protein, FKBP59, p59 protein
Reference Data
Protein Families Druggable Genome

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