Adeno-Associated Virus 2 / AAV2 (Replicase Rep 78, 68, 52, 40) Mouse Monoclonal Antibody [Clone ID: 303.9]
CAT#: AM09104PU-N
Adeno-Associated Virus 2 / AAV2 (Replicase Rep 78, 68, 52, 40) mouse monoclonal antibody, clone 303.9, Aff - Purified
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Specifications
| Product Data | |
| Clone Name | 303.9 |
| Applications | WB |
| Recommended Dilution | Immunoblotting: 1/50-1/100. |
| Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Recombinant AAV-2 Rep 78 protein, N-terminally truncated by 171 aa |
| Specificity | This antibody reacts with Replicase proteins (Rep78, Rep68, Rep52 and Rep40) of Human AAV-2-infected cells. Cross-reactivity with AAV serotypes 1, 3, 4, 5, and 6. A weak cross-reactivity is seen in some Human cell lines. |
| Formulation | Final solution contains 0.09% Sodium Azide, 0.5% BSA in PBS buffer, pH 7.4 State: Aff - Purified State: Lyophilized purified IgG fraction |
| Reconstitution Method | Restore in 1 ml distilled water |
| Purification | Affinity Chromatography on Protein A |
| Background | Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease and consequently the virus causes a very mild immune response. AAV can infect both dividing and non-dividing cells and may incorporate its genome into that of the host cell. These features make AAV a very attractive candidate for creating viral vectors for gene therapy, and for the creation of isogenic human disease models. Serotype 2 (AAV2) has been the most extensively examined so far. AAV2 presents natural tropism towards skeletal muscles, neurons, vascular smooth muscle cells and hepatocytes. |
| Synonyms | AAV-2 |
| Reference Data | |
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